| book details |

Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells: Mathematical Modeling and Experimental Observations

By (author) Iman Tavassoly

| on special |

normal price: R 4,375.95

Price: R 4,157.95

| add to trolley |

| book description |

This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitativeÂ fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.

| product details |

| other options |

Normally shipped | Available from overseas. Usually dispatched in 14 days
Readership Age |

Normal Price | R 4,640.95
Price | R 4,408.95 | on special |

| add to trolley |

| back |

| your trolley |

To view the items in your trolley please sign in.

| sign in |

| specials |

Bonsai Success in Southern Africa

Carl Morrow
Paperback / softback
160 pages
was: R 320.95
now: R 288.95
Stock is usually dispatched in 6-12 days from date of order

In this uniquely Southern African book, Carl Morrow and Keith Kirsten guide readers step by step into the magical realms of bonsai as a hobby, horticultural practice and art form.

| more |

| add to trolley |

The Ballerina and the Bull: Anarchist Utopias in the Age of Finance

Johanna Isaacson
Paperback / softback
288 pages
was: R 306.95
now: R 275.95
This title will take longer to obtain, and should be delivered in 6-8 weeks

Our moment has seen the resurgence of an anarchist sensibility, from the uprisings in Seattle in 1999 to the Occupy movement of 2011.

| more |

| add to trolley |

Fifteen Dogs

AndrÃ© Alexis
Paperback / softback
176 pages
was: R 280.95
now: R 252.95
Available from overseas. Dispatched in aprox 4-8 weeks as local supplier is out of stock

A pack of dogs are granted the power of human thought - but what will it do to them? A surprising and insightful look at the beauty and perils of consciousness.

| more |

| add to trolley |