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| book details |
Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells: Mathematical Modeling and Experimental Observations
By (author)
Iman Tavassoly
| on special |
normal price: R 4 534.95
Price: R 4 307.95
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| book description |
This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.
| product details |
Normally shipped |
Available from overseas. Usually dispatched in 14 days
Publisher |
Springer International Publishing AG
Published date |
25 Mar 2015
Language |
Format |
Hardback
Pages |
79
Dimensions |
235 x 155 x 0mm (L x W x H)
Weight |
0g
ISBN |
978-3-3191-4961-5
Readership Age |
BISAC |
technology / material science
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Helgoland: The Strange and Beautiful Story of Quantum Physics
Carlo Rovelli
Paperback / softback
208 pages
was: R 295.95
now: R 265.95
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The Order of Time
Carlo Rovelli
Paperback / softback
224 pages
was: R 295.95
now: R 265.95
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Originally published in Italian: L'ordine del tempo (Milan: Adelphi Edizioni, 2017).
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The Coming Wave: AI, Power and Our Future
Mustafa Suleyman
Paperback / softback
352 pages
was: R 295.95
now: R 265.95
Stock is usually dispatched in 6-12 days from date of order
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