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Microglia: Physiology, Pathophysiology and Therapeutic Potential

Edited by Marie-Ève Tremblay, Edited by Alexei Verkhratsky

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normal price: R 13,843.95

Price: R 13,150.95


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The past decade has witnessed a revolution in our understanding of microglia, especially since their roles in the healthy CNS have started to unravel. These cells were shown to actively maintain health, in concert with neurons and other types of CNS cells, providing further insight into their crucial involvement with diseases.  Edited by Drs. Marie-Ève Tremblay and Alexei Verkhratsky, Microglia: Physiology, Pathophysiology and Therapeutic Potential shares with the scientific and medical community the latest discoveries in the microglial research field, with a truly comprehensive collection of  chapters written by the top specialists across five continents. The book begins by explaining briefly what they are, from both historical and evolutionary points of view, and how they can be studied. The first section explains their physiological roles in the maturation, function, and plasticity of the CNS. The second section focuses on their general involvement in neuropathophysiology, and the third section on their critical implication in specific CNS diseases, including neurotrauma, neuropathic pain, ischemia and stroke, infectious diseases, autoimmune diseases, neurodevelopmental and neuropsychiatric disorders, substance use and addiction, sleep disorders, ageing, and neurodegenerative diseases. The fourth section presents their clinical potential as a targeted therapeutic tool for these  CNS diseases.

| product details |



Normally shipped | Forthcoming. We are not accepting backorders for this item yet
Publisher | Springer International Publishing AG
Published date | 30 Aug 2024
Language |
Format | Hardback
Pages | 644
Dimensions | 279 x 210 x 0mm (L x W x H)
Weight | 0g
ISBN | 978-3-0315-5528-2
Readership Age |
BISAC | medical / neurology


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