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| book details |
The Tumor Microenvironment
Edited by
Rebecca G. Bagley
| on special |
normal price: R 8,043.95
Price: R 7,641.95
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| book description |
The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial cells and pe- cytes, as well as inflammatory cells such as neutrophils, monocytes, macrophages, mast cells and eosinophils, and lymphocytes. The tumor cells also interact with stromal cells and with elements of the tissue extracellular matrix. What has been less appreciated is the role that these cells could have in modulating the growth, invasion, and metastasis of the tumor. Early on, the elements of what we now call the tumor microenvironment were considered to be more or less innocent bysta- ers to the role of the tumor cells as they grew and invaded local sites. Today, there is an increased understanding of the critical role of the tumor microenvironment as dramatically influencing the course of tumor development and dissemination. This volume represents a superb compilation of the latest thoughts and data regarding the role of each essential component of the tumor microenvironment in cancer development and progression. Perhaps, the earliest recognition of the role of nonmalignant cells as cancer re- lators was the recognition that lymphocytes can participate in what was termed “immune surveillance†in the 1960s. Our understanding of tumor immunity has improved markedly since then, and there are now successful clinical studies sh- ing the potential use of immune-based therapies in cancer treatment.
| product details |
Normally shipped |
Available from overseas. Delivery time is 14 - 21 days
Publisher |
Springer-Verlag New York Inc.
Published date |
6 Nov 2012
Language |
Format |
Paperback / softback
Pages |
770
Dimensions |
235 x 155 x 0mm (L x W x H)
Weight |
0g
ISBN |
978-1-4614-2660-8
Readership Age |
BISAC |
medical / oncology
| other options |
Normally shipped |
Available from overseas. Usually dispatched in 14 days
Readership Age |
Normal Price |
R 9,228.95
Price |
R 8,767.95
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Free Your Mind: The new world of manipulation and how to resist it
Laura Dodsworth
Paperback / softback
384 pages
was: R 300.95
now: R 270.95
Available from overseas. Dispatched in aprox 4-8 weeks as local supplier is out of stock
The Instant Sunday Times Bestseller Learn how to recognise and resist the daily attempts to control and manipulate your mind.
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The Silent Patient: The record-breaking, multimillion copy Sunday Times bestselling thriller and TikTok sensation
Alex Michaelides
Paperback / softback
352 pages
was: R 280.95
now: R 252.95
Available from overseas. Dispatched in aprox 4-8 weeks as local supplier is out of stock
With film rights snapped up by an Oscar winning Hollywood production company, rights sold in a world record 43 territories, and rave blurbs from David Baldacci, Lee Child and A.
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The Thing at 52
Mr. Ross Montgomery
Hardback
40 pages
was: R 363.95
now: R 345.95
Usually dispatched in 3 to 4 weeks as supplier is out of stock
The Thing at 52 is a beautiful picture book about friendship, loneliness and learning how to say goodbye.
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