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Alzheimer's Disease Drug Development: Research and Development Ecosystem

Edited by Jeffrey Cummings, Edited by Jefferson Kinney, Edited by Howard Fillit

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Alzheimer's Disease (AD) is a growing global public health challenge. The development of new therapies is urgently needed, and a complex ecosystem of organizations has grown to facilitate AD drug discovery and development. Masterfully collating information on the drug development ecosystem, this book emphasizes the contributions of each aspect in the pipeline with a uniform approach to chapters, enabling readers to access relevant information quickly. Topics covered include the use of non-clinical laboratory studies, biomarker development, artificial intelligence, design and management of clinical trials, and funding and financing models. Also discussed is the critical role of advocacy fundraising for drug development. With the approval of aducanumab, the function of the ecosystem has become apparent. This is a definitive overview of how the ecosystem works in transferring an AD drug from its discovery in the laboratory through clinical trial testing to regulatory review and eventual marketing.

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Bonsai Success in Southern Africa

Carl Morrow
Paperback / softback
160 pages
was: R 320.95
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In this uniquely Southern African book, Carl Morrow and Keith Kirsten guide readers step by step into the magical realms of bonsai as a hobby, horticultural practice and art form.

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Fifteen Dogs

AndrÃ© Alexis
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176 pages
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A pack of dogs are granted the power of human thought - but what will it do to them? A surprising and insightful look at the beauty and perils of consciousness.

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The Ballerina and the Bull: Anarchist Utopias in the Age of Finance

Johanna Isaacson
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288 pages
was: R 306.95
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Our moment has seen the resurgence of an anarchist sensibility, from the uprisings in Seattle in 1999 to the Occupy movement of 2011.

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