|
|
|
books
| book details |
Network Medicine: Complex Systems in Human Disease and Therapeutics
Edited by Joseph Loscalzo, Edited by Albert-László Barabási, Edited by Edwin K. Silverman, Contributions by Elliott M. Antman, Contributions by Michael A. Calderwood, Contributions by Benoit Charloteaux, Contributions by Clary B. Clish, Contributions by Michael E. Cusick, Contributions by Dawn Lisa Demeo, Contributions by John C. Earls
|
| on special |
normal price: R 1,902.95
Price: R 1,806.95
|
| book description |
Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. Network Medicine introduces this rapidly evolving field of medical research, which promises to revolutionize the diagnosis and treatment of human diseases. With contributions from leading experts that highlight the necessity of a team-based approach in network medicine, this definitive volume provides readers with a state-of-the-art synthesis of the progress being made and the challenges that remain. Medical researchers have long sought to identify single molecular defects that cause diseases, with the goal of developing silver-bullet therapies to treat them. But this paradigm overlooks the inherent complexity of human diseases and has often led to treatments that are inadequate or fraught with adverse side effects. Rather than trying to force disease pathogenesis into a reductionist model, network medicine embraces the complexity of multiple influences on disease and relies on many different types of networks: from the cellular-molecular level of protein-protein interactions to correlational studies of gene expression in biological samples. The authors offer a systematic approach to understanding complex diseases while explaining network medicine’s unique features, including the application of modern genomics technologies, biostatistics and bioinformatics, and dynamic systems analysis of complex molecular networks in an integrative context. By developing techniques and technologies that comprehensively assess genetic variation, cellular metabolism, and protein function, network medicine is opening up new vistas for uncovering causes and identifying cures of disease.
| product details |
Normally shipped |
Publisher | Harvard University Press
Published date | 1 Feb 2017
Language | English
Format | Hardback
Pages | 448
Dimensions | 235 x 156 x 0mm (L x W x H)
Weight | 0g
ISBN | 978-0-6744-3653-4
Readership Age |
BISAC | medical / diseases
| other options |
Normally shipped |
Readership Age |
Normal Price | R 2,074.95
Price | R 1,970.95
| on special |
|
|
|
To view the items in your trolley please sign in.
| sign in |
|
|
|
| specials |
|
|
Carl Morrow
Paperback / softback
160 pages
was: R 320.95
now: R 288.95
|
In this uniquely Southern African book, Carl Morrow and Keith Kirsten guide readers step by step into the magical realms of bonsai as a hobby, horticultural practice and art form.
|
|
André Alexis
Paperback / softback
176 pages
was: R 280.95
now: R 252.95
|
A pack of dogs are granted the power of human thought - but what will it do to them? A surprising and insightful look at the beauty and perils of consciousness.
|
Our moment has seen the resurgence of an anarchist sensibility, from the uprisings in Seattle in 1999 to the Occupy movement of 2011.
|
|
|
|
